General Information

  • ID:  hor004828
  • Uniprot ID:  P13737
  • Protein name:  Contraction-inhibiting peptide 2
  • Gene name:  N/A
  • Organism:  Mytilus edulis (Blue mussel)
  • Family:  NA
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Mytilus (genus), Mytilinae (subfamily), Mytilidae (family), Mytiloidea (superfamily), Mytilida (order), Pteriomorphia, Autobranchia (subclass), Bivalvia (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0005179 hormone activity
  • GO BP:  GO:0007165 signal transduction
  • GO CC:  NA

Sequence Information

  • Sequence:  GAPMFV
  • Length:  6(1-6)
  • Propeptide:  GAPMFV
  • Signal peptide:  NA
  • Modification:  T6 Valine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Inhibitory action on contractions in several molluscan muscles.
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor004828_AF2.pdbhor004828_ESM.pdb

Physical Information

Mass: 71013 Formula: C29H44N6O7S
Absent amino acids: CDEHIKLNQRSTWY Common amino acids: AFGMPV
pI: 6.11 Basic residues: 0
Polar residues: 1 Hydrophobic residues: 3
Hydrophobicity: 145 Boman Index: 1212
Half-Life / Aliphatic Index: 30 hour Aliphatic Index: 65
Instability Index: 1371.67 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  3377776
  • Title:  Structures and actions of Mytilus inhibitory peptides.